Office of Research & Technology Transfer

 

The list below includes examples of start-up companies have been formed based on research and technology efforts at The University of Texas Health Science Center at Houston.

 

University of Texas Health Science Center at Houston
Examples of Start-up Companies

 

 

 

 

Advanced Guidance Systems, LLC
logoadvanced guidance

Description

 

Guide View System

UT Faculty Involved

 

M. Sriram Iyengar, Ph.D

Location

 

Houston, TX

Year Formed

 

 

Other Information

 

Software related to a system for developing and delivering structured, interactive, multi-modal guidelines with a versatile interdisciplinary application and means of employment.

 

Ampholife Technologies, Inc.

Description

 

Large-scale purification of biological materials

UT Faculty Involved

 

L. Scott Rodkey

Location

 

Houston, TX

Year Formed

 

1988

Other Information

 

Currently manufactures the ATIsolator, a high-volume protein purification instrument that utilizes a fluid-phase isoelectric focusing format for high-resolution preparative purification of biomolecules and manufactures a series of ampholyte compounds.

 

 

Description

Cerevast Therapeutics, Inc. is a life sciences company with primary emphasis in the field of sonolysis for the treatment of vascular thrombus disorders. Based on technology created by Dr. Andrei Alexandrov, Cerevast plans to market a patented, innovative, operator-assisted transcranial doppler (TCD) ultrasound device with an initial therapeutic focus in the field of acute ischemic stroke. The company plans to leverage the unique geometry of the TCD device in combination with thrombolytics or proprietary microsphere technology as a non-invasive therapy for disrupting blood clots and restoring blood flow in the vasculature of the brain.

 
 

 

Description

 

Medical Device - Dematology - Cryosurgery CryoPen Surgical System - Linear compression cooling technology, does not require handling of dangerous cryogenic gases - penpoint precision and socnistent freeze temperature reduces the risk of burns.

 

 

Location

 

Corpus Christi, Tx

 

 

 

Endothelix, Inc
logo endothelix

 

Description

 

 

Monitoring technology for cardiovascular health

Location

 

Houston, TX

Year Formed

 

2003

Other Information

 

Endothelix was awarded a $1 million grant from the State of Texas Emerging Technologies Fund for the development of its VENDYS™ system, for the measurement of vascular reactivity, and endothelial dysfunction. Recently VENDYS™ was approved by the FDA for commercial sale.

 

 

 

 

 

EMIT Corporation

Description

 

EMIT Corporation (Emergency Medical Interventional Technologies Corporation) is developing trauma care products based on innovative devices developed by UTHSC-H’s Drs. Charles Cox, Jr. and Brijesh Gill from the Departments of Pediatric Surgery and Surgery, respectively. EMIT’s first product includes a novel, patent-protected, portable fluid warmer to deliver therapeutic temperature management to patients experiencing hypothermia anywhere in the world and much sooner after injury.

IsoVax Therapeutics

Description

 

IsoVax Therapeutics is an early stage, drug-discovery biotech company involved in the identification and production of conformational protein isomers of important proteins involved in the diagnosis and/or treatment of disease which are unique targets for developing diagnostic and therapeutic antibodies and vaccines.




logo leonardo

Description

 

Multi-stage nanovector drug delivery technology to facilitate chemotherapy and biological anti-cancer agent delivery

 

Year Formed

 

2008

 

UT Faculty Involved

 

Mauro Ferrari, Ph.D.

 

Location

 

Pasadena, CA

 

Year Formed

 

2007

 

Other Information

 

The Company’s first target market is drug refractory breast cancer.

logo life cell

     

 

 

Description

 

 

 

Biologically-based products for the repair and replacement of human tissue

 

UT Faculty Involved

 

Dr. John Linner

Location

 

Branchburg, NJ

Year Formed

 

1986

 

Other Information

 

LifeCell’s current products include ALLODERM®, a regenerative tissue matrix, for plastic reconstruction. LIFC had an IPO in 1992, and in 2008, projected revenues are estimated at $233.0 million. LIFC recently announced its acquisition by Kinetics Concepts Inc. for $1.7 billion.

 

 

 

 

 

Marval Biosciences, Inc.
logo marvel

Description

 

Marval Biosciences, Inc. is developing the next generation contrast agents for high speed, high resolution CT scanners.

UT Faculty Involved

 

Ananth Annapragada

Location

 

 

Year Formed

 

2007

Other Information

 

Marval’s agents remain in the circulation for hours, facilitating continuous follow-up imaging in patients with evolving vascular crises including myocardial infarcts, stroke, and pulmonary emboli. Series A funding of $1.4 Million as well as SBIR Phase II funding from the NIH.

NanoMedical Systems, Inc.
logo nanomedical

Description

 

Nano-engineered diffusion delivery systems for drug delivery. Personalized Molecular Drug delivery System (PMDS) is a small drug delivery device that is implanted under the skin for slow and consistent release of a therapeutic agent over many weeks or months. A non channel delivery system (nDS) embodied on a silicon chip regulates the flow of therapeutic molecules.

 

UT Faculty Involved

 

Mauro Ferrari, Ph.D.

Location

 

Austin, TX

Year Formed

 

2008

Other Information

 

NanoMedical Systems (NMS) is one of the first convergent technology companies, integrating semiconductor, biotechnology, MEMS/NEMS, nano-materials, and pharmaceutical sciences in its products. Operates in the drug delivery field.

 

PLx Pharma, Inc.
logo plx

 

     

Description

 

PC-NSAID based medications used for pain, inflammation, and cardiovascular treatment  

UT Faculty Involved

 

Leonard Lichtenberger

Location

 

Houston, TX

Year Formed

 

2002

Other Information

 

PLx completed four clinical trials with two lead products, and a third product recently received IND approval. PLx raised over $11 million, and has sponsored $4M in research to UTHSC-H and UT Medical Branch.

 

       

Protein Institute Inc. (Isovax)

 

Description

 

Protein identification for disease, diagnosis/treatment

 

UT Faculty Involved

 

Rowen Chang

 

Location

 

Houston, TX

 

Year Formed

 

2001

 

Other Information

 

PII possesses a series of biologically significant protein structural isomer profiles, which may lead to the development of new therapeutics and/or diagnostics for CNS diseases and cytokine disorders.

 

 

 

Simulation Education Services, Inc.

Description

 

Web-based disaster exercise technology

UT Faculty Involved

 

Scott Lillibridge

Location

 

Des Moines, IA

Year Formed

 

2006

Other Information

 

SES’s technology targets health care responders and other vital response sectors in areas where they have health related responsibilities, such as law enforcement, EMS, fire services, preparedness training in bioterror, mass casualty, natural disaster, and pandemic flu. SES webinars feature nationally known speakers dealing with topics pertinent to the disaster preparedness community to provide exercises and assessment needs.

 

Telemedicus, Inc.

logo telemedicus

Description

 

Products for fixed, mobile and deployable telemedicine applications that effectively places a “virtual physician” at a remote location.

UT Faculty Involved

 

James "Red" Duke, Doug Tindall

Location

 

Houston, TX

Year Formed

 

2006

Other Information

 

Telemedicus, Inc. targets a market of 40,000 ambulances nationwide, as well as emergency care facilities and remote or dislocated medical facilities. The Telemedicus technology operated in New Orleans after Katrina and is in operation in Houston and in Liberty Counties.

 

TexTeach, Inc.

Description

 

Care of Aging Videos for Nurse training

logo texteach

UT Faculty Involved

 

Nancy Bergstrom and Vaunette Fay

Location

 

Houston, TX

Year Formed

 

2005

Other Information

 

Two products on the market

 

 

 

Vanjan, Inc.

logo vanjan

Description

 

Novel treatment to control mycobacterium tuberculosis infections (MTB).

UT Faculty Involved

 

Dr. James Stoops

Location

 

Houston, TX

Year Formed

 

2007

Other Information

 

Vanjan’s novel treatment is ideal for use in third world countries because of the inexpensive cost.  Vanjan is currently beginning clinical trials to test treatment efficacy.

 

 

logo volcano

 

Description

 

Cardiology medical devices for the diagnosis and treatment of coronary plaque

UT Faculty Involved

 

James T. Willerson and Ward S. Casscells

Location

 

Rancho Cordova, CA

Year Formed

 

2001

Other Information

 

Volcano Inc. specializes in the manufacture of intravascular ultrasound and other devices for use in the assessment of heart and vascular disease. Volcano had an Initial Public Offering (IPO) in June 2006, based, in part, on the value of UTHSC-H technology.

Windmill Cardiovascular Systems, Inc
logo windmill

Description

 

 Left ventricular assist device and a total artificial heart

 

UT Faculty Involved

 

Richard Smalling

 

Location

 

Austin, TX

 

Year Formed

 

2005

 

Other Information

 

The WCS blood pump, TORVADTM, eliminates inlet and outlet valves while providing capability for control and synchronization with the native heart over a wide range of blood flows from near steady flow to pulsatile flow. WCS raised over $1.7 million with a commitment of approx. $3 million through 2010.

 

Your Doctor Program, Inc.
logo dr program

 

Description

 

Patient outcomes management system

UT Faculty Involved

 

Kim Dunn

Location

 

Houston, TX

Year Formed

 

2001

Other Information

 

Involves numerous local, state, and national organizations

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